This information provides a general overview and may not apply to everyone. Talk to your family doctor to find out if this information applies to you and to get more information on this subject.
Human papillomavirus HPV is a common sexually transmitted infection that can cause genital warts and certain types of cancer. A Pap smear is a medical exam used to determine if a woman has cervical cancer. Visit The Symptom Checker. Read More. Abnormal Uterine Bleeding. Vaginal Discharge. Polycystic Ovary Syndrome.
Alcohol Abuse. Home Diseases and Conditions Cervical Dysplasia. Table of Contents. What is cervical dysplasia? What causes cervical dysplasia? How is cervical dysplasia diagnosed? Can cervical dysplasia be prevented or avoided? Delay the onset of sexual activity as long as possible or until you are in a long-term relationship. Use a condom whenever you have sex. Have as few sexual partners as possible. Through the efforts of a team of investigators in the Johns Hopkins Center for Cervical Dysplasia, several clinical trials testing immune therapies for HPV disease are currently open.
The development of these HPV-targeted immune therapies, chronicled in over 20 publications in leading biomedical research journals, emerged from a team of translational investigators in three different disciplines: immunology, gynecologic pathology, and gynecology. The initial generation of HPV vaccines involved the use of targeting signals that made HPV antigens more visible to the immune system. In animal models, these vaccines made strong immune responses against HPV.
In addition, strategic collaborations with a number of companies are paving the way to the development of combination immunotherapies with even greater potential efficacy. It is our goal to develop a combinatorial HPV immunotherapy approach that could be applied to all women with established HPV infections, that would ultimately eliminate the need for the complex and expensive screening, long-term follow-up, and surgical interventions currently employed to manage HPV disease.
The identification of specific HPV antigens makes this disease an ideal model to develop antigen-specific immunotherapies for other chronic viral diseases, such as hepatitis, and ultimately, non-virus-associated cancers.
Request your next appointment through My Chart! Whether you're crossing the country or the globe, we make it easy to access world-class care at Johns Hopkins. Contact us or find a patient care location. Privacy Statement. Non-Discrimination Notice. All rights reserved. Skip Navigation. Folate and B12 deficiencies have been associated with increased HPV infection.
This treatment is performed two times per week for approximately six weeks. The role of smoking and alcohol intake in the development of high-grade squamous intraepithelial lesions among high-risk HPV-positive women. National Center for Biotechnology Information.
Accessed April 15, A look at cervical cancer. Low serum and red blood cell folate are moderately, but nonsignificantly associated with increased risk of invasive cervical cancer. J Nutr. Schiff MA, et al. Serum carotenoids and risk of cervical epithelial neoplasia in southwestern American women. Cancer Epidemiol Biomarkers Prev. Int J Gynaecol Obstet. Epub Nov Marshall K. Cervical dysplasia: early intervention.
Altern Med Rev. Chemoprevention of chemically-induced mammary carcinogenesis by indolecarbinol. Anticancer Res ; Placebo-controlled trial of indolecarbinol in the treatment of CIN. Error Include a valid email address. To provide you with the most relevant and helpful information and to understand which information is beneficial, we may combine your e-mail and website usage information with other information we have about you.
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